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Smith & Wesson .45 ACP Handguns

In the world of firearms, few names resonate with the same authority as Smith & Wesson. Known for their precision engineering and robust design, Smith & Wesson handguns chambered in .45 ACP offer a compelling blend of power and reliability. These handguns are crafted for those who demand performance in every shot, whether for personal defense or competitive shooting. The .45 ACP caliber is celebrated for its stopping power, making it a preferred choice among enthusiasts and professionals alike. Explore our selection of Smith & Wesson handguns to find models that embody the legacy of innovation and excellence. Each firearm is a testament to Smith & Wesson's commitment to quality, ensuring that you have a reliable companion in any scenario. For a broader range of options, visit our Handguns section, where precision meets performance in every caliber.

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17 Product(s)
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Smith & Wesson 108411 1911 Single .45 ACP 5" 8+1 Laminate Wood Grip Stainless

Smith & Wesson 108411 1911 Single .45 ACP 5" 8+1 Laminate Wood Grip Stainless
$1441 69
In Stock
Smith & Wesson M&P .45 ACP Shield. 3.3" Barrel No Thumb Safety 11531

Smith & Wesson M&P .45 ACP Shield. 3.3" Barrel No Thumb Safety 11531
$498 63
In Stock
Smith & Wesson 108483 1911SC 45 ACP E Series SS Black 8rd

Smith & Wesson 108483 1911SC 45 ACP E Series SS Black 8rd

$1495 04
In Stock
Smith & Wesson 13586 M&P45 M2.0 5.12" Optic Ready 10-SH Threaded Black

Smith & Wesson 13586 M&P45 M2.0 5.12" Optic Ready 10-SH Threaded Black

$619 58
In Stock
Only 5 Left!
Smith & Wesson 10270 1911 Engraved Single 45 ACP 5" 8+1 Laminate Wood Grip Stainless Steel

Smith & Wesson 10270 1911 Engraved Single 45 ACP 5" 8+1 Laminate Wood Grip Stainless Steel
$1259 84
In Stock
Only 4 Left!
Smith & Wesson 180022 M&P Shield DA/SA .45 ACP 3.3" 6+1/7+1 Black Polymer Grip

Smith & Wesson 180022 M&P Shield DA/SA .45 ACP 3.3" 6+1/7+1 Black Polymer Grip
$498 63
In Stock
Smith & Wesson 170344 1911 Performance Center DAO 45 ACP 4.25" 8+1 Custom Wood G10 Grip Black

Smith & Wesson 170344 1911 Performance Center DAO 45 ACP 4.25" 8+1 Custom Wood G10 Grip Black
$1632 24
In Stock
Only 5 Left!
Smith & Wesson 170343 1911 Single .45 ACP 5" 8+1 Custom Wood G10 Grip Stainless

Smith & Wesson 170343 1911 Single .45 ACP 5" 8+1 Custom Wood G10 Grip Stainless
$1632 24
In Stock
Smith & Wesson 108485 1911SC 45 ACP 4.25 E Series NS DUO Tone 8rd

Smith & Wesson 108485 1911SC 45 ACP 4.25 E Series NS DUO Tone 8rd

$1495 04
In Stock
Smith & Wesson 108482 1911 45 ACP E Series 5 SS Wood Grips 8rd

Smith & Wesson 108482 1911 45 ACP E Series 5 SS Wood Grips 8rd

$1009 40
In Stock
Smith & Wesson 178020 1911 Pro Single .45 ACP 3" 7+1 Black Synthetic Grip Black

Smith & Wesson 178020 1911 Pro Single .45 ACP 3" 7+1 Black Synthetic Grip Black

Out of Stock
Smith & Wesson 11526 M&P M2.0 Double 45 ACP 4.6" 10+1 TS 3Dot Black Interchangeable Backstrap Grip Black Armornite Stainless Steel

Smith & Wesson 11526 M&P M2.0 Double 45 ACP 4.6" 10+1 TS 3Dot Black Interchangeable Backstrap Grip Black Armornite Stainless Steel

Out of Stock
Smith & Wesson M&P45SHLD 12473 PFMC 45 3.3 PT 2.0 Hiviz NTS

Smith & Wesson M&P45SHLD 12473 PFMC 45 3.3 PT 2.0 Hiviz NTS

Out of Stock
Smith & Wesson M&P 2.0 Semi-Automatic .45 ACP Pistol, Black, 4.5" Barrel, 1913 Picatinny Rail - Law Enforcement Trade In - USED - (1) 10 Round Magazine

Smith & Wesson M&P 2.0 Semi-Automatic .45 ACP Pistol, Black, 4.5" Barrel, 1913 Picatinny Rail - Law Enforcement Trade In - USED - (1) 10 Round Magazine

Out of Stock
Smith & Wesson 4506-1 Semi-Automatic .45 ACP Pistol, 5" Barrel, 8+1 Capacity - Stainless Steel - 4506-1 - Very Good Condition - Used

Smith & Wesson 4506-1 Semi-Automatic .45 ACP Pistol, 5" Barrel, 8+1 Capacity - Stainless Steel - 4506-1 - Very Good Condition - Used

Out of Stock
Smith & Wesson 4516 Semi-Automatic .45 ACP Pistol, 3.75" Barrel, 7+1 Capacity - Stainless Steel - 4516 - Used Good Condition

Smith & Wesson 4516 Semi-Automatic .45 ACP Pistol, 3.75" Barrel, 7+1 Capacity - Stainless Steel - 4516 - Used Good Condition

Out of Stock
Smith & Wesson 457 Semi-Automatic .45 ACP Pistol, 3.75" Barrel, 7+1 Capacity - Blued - 457 - Used Good Condition

Smith & Wesson 457 Semi-Automatic .45 ACP Pistol, 3.75" Barrel, 7+1 Capacity - Blued - 457 - Used Good Condition
Out of Stock
17 Product(s)
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